Triple negative breast cancer (TNBC) is a type of breast cancer that does not have receptors for the hormones estrogen and progesterone, or the protein HER2. It is an aggressive form of cancer that is more likely to spread to other parts of the body and is more difficult to treat than other types of breast cancer.
Recent research has focused on understanding the biology of TNBC and developing new treatments. One area of research is looking at the genetic mutations that are associated with TNBC. Researchers have identified several genes that are linked to TNBC, including BRCA1 and BRCA2. These genes are involved in DNA repair and can increase the risk of developing TNBC.
Other research is looking at the role of immunotherapy in treating TNBC. Immunotherapy is a type of treatment that uses the body’s own immune system to fight cancer. Studies have shown that immunotherapy can be effective in treating TNBC, although more research is needed to understand how it works and how it can be used most effectively.
Researchers are also looking at the role of targeted therapies in treating TNBC. Targeted therapies are drugs that target specific molecules in cancer cells, such as proteins or enzymes. These drugs can be used to stop the growth and spread of cancer cells. Several targeted therapies are currently being studied for their potential to treat TNBC, including PARP inhibitors and PI3K inhibitors.
Finally, researchers are looking at the role of lifestyle factors in preventing and treating TNBC. Studies have shown that maintaining a healthy weight, exercising regularly, and eating a healthy diet can reduce the risk of developing TNBC. Additionally, research has shown that lifestyle factors can also help to reduce the risk of recurrence and improve survival rates in people with TNBC.
Overall, research into TNBC is ongoing and there is still much to learn about this type of cancer. However, the latest research is providing new insights into the biology of TNBC and potential treatments. With continued research, it is hoped that new treatments and strategies for preventing and treating TNBC will be developed in the future.